منابع مشابه
1358 Helper and Suppressor T Cell Activation by Pvp
Type 2 antigens such as polyvinylpyrrolidone (PVP), 1 type III pneumococcal polysaccharide ($3), and dinitrophenyl (DNP)-ficoll characteristically elicit antibody responses in mice that consist almost entirely of antibodies of the IgM and IgG3 isotypes (1-4). Type 2 antigens also are generally unable to prime mice to produce I gG 1 and IgG2 antibodies after secondary challenge, i.e. they are un...
متن کاملFibroblast and T cells conditioned media induce maturation dendritic cell and promote T helper immune response
Dendritic cells (DCs) induce pathogen-specific T cell responses. We comprehensively studied the effects of addition of maturation stimulus, fibroblasts (fibroblast conditioned medium), PHA activated T cells (T cell conditioned medium), and mixture of fibroblast & PHA activated T cells (FCM-TCCM) conditioned media on maturation of DCs. Monocytes were cultured with GM-CSF and IL-4 for five days. ...
متن کاملT-cell differentiation: Commitment factors for T helper cells
The immune system is designed to eradicate a large variety of invading pathogens with minimum immunopathology. T helper cells, also known as CD4+ T cells, may be subdivided into the T helper 1 (Th1) and the T helper 2 (Th2) subsets, which produce distinct profiles of cytokines [1,2]. These Th1 and Th2 cells have opposing roles, regulating immune responses to intracellular and extracellular path...
متن کاملSeparation of helper T cells from suppressor T cells expressing different Ly components. I. Polyclonal activation: suppressor and helper activities are inherent properties of distinct T-cell subclasses
Concanavalin A, a nonspecific polyclonal activator of T lymphocytes, activates Lyl and Ly23 subclasses to the same degree. After activation, the Ly23 subclass, but not the Lyl subclass, has the following properties: (a) Suppression of the antibody response to sheep erythrocytes (SRBC) in vitro. (b) Production of a soluble factor that suppresses the anti-SRBC response in vitro. (c) Suppression o...
متن کاملThe Expression of T-Helper Associated Transcription Factors and Cytokine Genes in Pre-Eclampsia
Background: Pre-eclampsia (PE) is known as a main factor contributing to fetomaternal mortality, which might affect 2-8% of all pregnancies after the twentieth week of gestation. The balance of T helper subsets is essential to sustain a normal pregnancy and preventing fetomaternal complications. Objective: To investigate differences in the levels of transcription factors and cytokine gene e...
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ژورنال
عنوان ژورنال: Springer Seminars in Immunopathology
سال: 1980
ISSN: 0344-4325,1432-2196
DOI: 10.1007/bf00199927